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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SYT6 All Species: 8.79
Human Site: S224 Identified Species: 19.33
UniProt: Q5T7P8 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.5
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T7P8 NP_995320.1 510 57325 S224 V D G E D A K S E A T K S C G
Chimpanzee Pan troglodytes XP_528725 523 59120 G223 Q K S V D S E G N Q N E D V K
Rhesus Macaque Macaca mulatta XP_001111496 528 59228 S224 V D G D D A K S E A T K S C G
Dog Lupus familis XP_540243 510 57041 S224 V D G D D A K S E A A K S C G
Cat Felis silvestris
Mouse Mus musculus Q9R0N8 511 57171 K224 S V D G D D A K S E A A K S C
Rat Rattus norvegicus Q62746 511 57160 K224 S V D G D E A K S E A A K S C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507537 468 53664 R191 V D T D D G R R T N S R A C G
Chicken Gallus gallus P47191 424 47487 Q149 V E K L G K I Q Y S L D Y D F
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_691385 676 75366 A366 Y K Q S T M E A E D S S K N D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P21521 474 53246 K199 K L G R L N F K L E Y D F N S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34693 441 49885 K166 K L G R I Q Y K L D Y D F Q Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 63.8 95.2 94.9 N.A. 96.4 95.8 N.A. 53.3 35.6 N.A. 56.3 N.A. 32.5 N.A. 33.5 N.A.
Protein Similarity: 100 76.2 96 96.4 N.A. 97.4 97.4 N.A. 68.2 51.5 N.A. 63.9 N.A. 52.9 N.A. 51.9 N.A.
P-Site Identity: 100 6.6 93.3 86.6 N.A. 6.6 6.6 N.A. 33.3 6.6 N.A. 6.6 N.A. 6.6 N.A. 6.6 N.A.
P-Site Similarity: 100 26.6 100 93.3 N.A. 6.6 6.6 N.A. 66.6 20 N.A. 26.6 N.A. 6.6 N.A. 6.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 28 19 10 0 28 28 19 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 37 19 % C
% Asp: 0 37 19 28 64 10 0 0 0 19 0 28 10 10 10 % D
% Glu: 0 10 0 10 0 10 19 0 37 28 0 10 0 0 0 % E
% Phe: 0 0 0 0 0 0 10 0 0 0 0 0 19 0 10 % F
% Gly: 0 0 46 19 10 10 0 10 0 0 0 0 0 0 37 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % I
% Lys: 19 19 10 0 0 10 28 37 0 0 0 28 28 0 10 % K
% Leu: 0 19 0 10 10 0 0 0 19 0 10 0 0 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 10 0 0 10 10 10 0 0 19 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 10 0 10 0 0 10 0 10 0 10 0 0 0 10 10 % Q
% Arg: 0 0 0 19 0 0 10 10 0 0 0 10 0 0 0 % R
% Ser: 19 0 10 10 0 10 0 28 19 10 19 10 28 19 10 % S
% Thr: 0 0 10 0 10 0 0 0 10 0 19 0 0 0 0 % T
% Val: 46 19 0 10 0 0 0 0 0 0 0 0 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 0 0 10 0 10 0 19 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _